The role of flavonoid antioxidant, morin in improving procarbazine-induced oxidative stress on testicular function in rat
Background: Procarbazine (PCZ) is an effective chemotherapeutic drug used in the
treatment of lymphoma; however, oxidative stress–mediated testicular toxicity is a major side
effect. Recently, therapeutic intervention using flavonoids against oxidative stress–related
pathologies is gaining more attention. Morin (MOR) is a natural flavonoid with proven
antioxidant activity. This study was designed therefore to evaluate the potential role of MOR
in ameliorating PCZ-induced testicular oxidative stress and altered sperm quality in rat …
treatment of lymphoma; however, oxidative stress–mediated testicular toxicity is a major side
effect. Recently, therapeutic intervention using flavonoids against oxidative stress–related
pathologies is gaining more attention. Morin (MOR) is a natural flavonoid with proven
antioxidant activity. This study was designed therefore to evaluate the potential role of MOR
in ameliorating PCZ-induced testicular oxidative stress and altered sperm quality in rat …
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