The role of impaired neuronal communication in neurological disorders
Current opinion in neurology, 2007•journals.lww.com
… The large-scale organization of the brain into distributed networks has important implications
for our understanding of central nervous system disorders and brain–behavior relationships
after brain injury. Some of these implications were foreseen many years ago by early … It is the
rule that cognitive functions are almost never normal in patients with a focal brain injury.
Whereas traditional explanations invoke non-neuronal factors such as edema, vascular
dysregulation, and so on, a network perspective explains this multitude of problems by invoking …
for our understanding of central nervous system disorders and brain–behavior relationships
after brain injury. Some of these implications were foreseen many years ago by early … It is the
rule that cognitive functions are almost never normal in patients with a focal brain injury.
Whereas traditional explanations invoke non-neuronal factors such as edema, vascular
dysregulation, and so on, a network perspective explains this multitude of problems by invoking …
Summary
A network perspective is fundamental to appreciating the pathophysiology of brain injury at the systems level and the underlying mechanisms of recovery, and for developing novel strategies of rehabilitation.
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