The role of the βDELSEED-loop of ATP synthase
N Mnatsakanyan, AM Krishnakumar, T Suzuki… - Journal of Biological …, 2009 - ASBMB
ATP synthase uses a unique rotational mechanism to convert chemical energy into
mechanical energy and back into chemical energy. The helix-turn-helix motif, termed"
DELSEED-loop," in the C-terminal domain of the β subunit was suggested to be involved in
coupling between catalysis and rotation. Here, the role of the DELSEED-loop was
investigated by functional analysis of mutants of Bacillus PS3 ATP synthase that had 3–7
amino acids within the loop deleted. All mutants were able to catalyze ATP hydrolysis, some …
mechanical energy and back into chemical energy. The helix-turn-helix motif, termed"
DELSEED-loop," in the C-terminal domain of the β subunit was suggested to be involved in
coupling between catalysis and rotation. Here, the role of the DELSEED-loop was
investigated by functional analysis of mutants of Bacillus PS3 ATP synthase that had 3–7
amino acids within the loop deleted. All mutants were able to catalyze ATP hydrolysis, some …
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