The structural properties of DNA-linked gold nanoparticle materials were examined using
synchrotron small-angle X-ray scattering. The materials are composed of 12 or 19 nm
diameter gold particles modified with 3 'or 5 'alkylthiol-capped 12-base oligonucleotides and
linked with complementary oligonucleotides. Structure factors were derived from scattering
intensities, and nearest-neighbor distances were determined from the primary peak in the
pair distance distribution functions. The separation between particles was found to increase …

Recently, there has been considerable effort aimed at developing str dimensional functional
ategies for assembling nanoparticles int structures [1]. Because o two-and threee dependent
upon their xhibit collective phy ar sical and chemical pr chitectural parameters [1–8], the
ability operties such structur that ar es to e deliber essential f atel or y organize nanoparticles
into a preconceived structure is