The synaptic basis of GABAA, slow

MI Banks, TB Li, RA Pearce - Journal of Neuroscience, 1998 - Soc Neuroscience
… population of events that resemble GABA A,fast in their rise and decay kinetics. The absence
of slow sIPSCs calls into question the synaptic basis of GABA A,slow . We present evidence …

GABAA, slow: causes and consequences

M Capogna, RA Pearce - Trends in neurosciences, 2011 - cell.com
… For the purposes of this review we define GABA A,slow as a spontaneous or evoked GABA
A -receptor-mediated phasic current with a decay constant of > 30 ms. We focus primarily on …

Different transmitter transients underlie presynaptic cell type specificity of GABAA,slow and GABAA,fast

J Szabadics, G Tamás, I Soltesz - Proceedings of the …, 2007 - National Acad Sciences
… Although unusually slow GABA A IPSCs, lasting for tens of … GABA A,slow IPSCs originate
from a specialized interneuron called neurogliaform cells. Compared with classical GABA A,fast …

Slow phases of GABAA receptor desensitization: structural determinants and possible relevance for synaptic function

MT Bianchi, RL Macdonald - The Journal of physiology, 2002 - Wiley Online Library
… the slow phases of desensitization. Finally, to investigate the possible role of slow desensitization
in synaptic … receptors can accumulate in slowly equilibrating desensitized states during …

GABAA Receptor α5 Subunits Contribute to GABAA,slow Synaptic Inhibition in Mouse Hippocampus

ED Zarnowska, R Keist, U Rudolph… - Journal of …, 2009 - journals.physiology.org
GABA A R-mediated synaptic inhibition in mouse hippocampus. Our findings indicate that α5
subunits do contribute to a subset of GABA A,slow synaptic … to GABA A,fast synaptic currents…

Slow GABAAmediated synaptic transmission in rat visual cortex

MP Sceniak, MB MacIver - BMC neuroscience, 2008 - Springer
… neocortex displays synaptic responses with slow GABA A receptor … GABA A slow currents
occur both spontaneously and as evoked responses in the neocortex. Cortical GABA A slow

Networks of interneurons with fast and slow γ-aminobutyric acid type A (GABAA) kinetics provide substrate for mixed gamma-theta rhythm

JA White, MI Banks, RA Pearce… - Proceedings of the …, 2000 - National Acad Sciences
… Kinetics of inhibitory synapses reflected values measured at 35C. For GABA A,fast synapses
For GABA A,slow synapses, we used rising time constants of 5 ms and falling time constants …

GABAA-Mediated IPSCs in Piriform Cortex Have Fast and Slow Components With Different Properties and Locations on Pyramidal Cells

A Kapur, RA Pearce, WW Lytton… - Journal of …, 1997 - journals.physiology.org
… Finally, evidence is presented that the slow GABA A -mediated IPSC component … slow GABA
A component in regulation of synaptic plasticity. The lack of susceptibility of the fast GABA A

Interactions between distinct GABAA circuits in hippocampus

MI Banks, JA White, RA Pearce - Neuron, 2000 - cell.com
… of spontaneous GABA A,… to GABA A,slow IPSCs, and SL-M stimuli elicit GABA A,slow IPSCs
in interneurons. We conclude that GABA A,slow cells inhibit both pyramidal cells and GABA A

The cellular, molecular and ionic basis of GABAA receptor signalling

M Farrant, K Kaila - Progress in brain research, 2007 - Elsevier
… the synaptic concentration transient) or the effects of agents such as chlorpromazine or protons
that slow … the exposure of synaptic receptors to GABA is brief) indicate a time constant of …