[HTML][HTML] Therapeutic vaccines for high-risk HPV-associated diseases
Cancer is the second leading cause of death worldwide, and it is estimated that Human
papillomavirus (HPV) related cancers account for 5% of all human cancers. Current HPV
vaccines are extremely effective at preventing infection and neoplastic disease; however,
they are prophylactic and do not clear established infections. Therapeutic vaccines which
trigger cell-mediated immune responses for the treatment of established infections and
malignancies are therefore required. The E6 and E7 early genes are ideal targets for …
papillomavirus (HPV) related cancers account for 5% of all human cancers. Current HPV
vaccines are extremely effective at preventing infection and neoplastic disease; however,
they are prophylactic and do not clear established infections. Therapeutic vaccines which
trigger cell-mediated immune responses for the treatment of established infections and
malignancies are therefore required. The E6 and E7 early genes are ideal targets for …
[引用][C] Therapeutic vaccines for high-risk HPV-associated diseases. Papillomavirus Res 5: 46–58
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