We draw on psychological ownership literature, the social support perspective, and stress research to examine the impact of psychological ownership toward a venture, family support, and hindrance-related stress on entrepreneurs’ venture exit decisions. Using an experimental study on 157 entrepreneurs through Amazon Mechanical Turk, we found that both family support and psychological ownership reduce hindrance-related stress, which is positively associated with the likelihood of venture exit. Furthermore, the effect of family support on the likelihood of venture exit is fully mediated by hindrance-related stress, whereas the effect of psychological ownership on the likelihood of venture exit is partially mediated by hindrance-related stress.