confers an advantage in innate immune defense but may signal an increased risk of
atherosclerosis. We determined whether recently discovered genetic variants of toll-like
receptor 4 (TLR4) that confer differences in the inflammatory response elicited by bacterial
lipopolysaccharide are related to the development of atherosclerosis. Methods As part of the
five-year follow-up in the Bruneck (Italy) Study, we screened 810 persons in the study cohort …