The relationship between demographics (generation status, age, gender, education level) and ethnicity-related stressors, namely, perceived discrimination, stereotype confirmation concern, and own-group conformity pressure, and the life satisfaction of 115 Latino college students was examined. A hierarchical multiple regression analysis indicated the demographic and ethnicity-related stressors collectively significantly predicted life satisfaction. Specifically, older students, men, students who reported lower stereotype confirmation concern and own-group conformity pressure had significantly higher life satisfaction than younger students, women, and students who reported higher stereotype confirmation concern and own-group conformity pressure, respectively. Implications for college personnel and future research examining the consequences of ethnicity-related stressors on Latino college students’ well-being are delineated.