… In summary, resin 4 represents a substantial progress toward the conceptual development
of an artificial aldolase. The particular functional arrangement in the monomer plus linker …

… artificial ATP-free in vitro synthetic enzymatic biosystems were constructed to produce GA3P
and DHAP from starch and pyrophosphate (Figure 1), thus facilitating aldolase-… aldolases to …

… Synthetic chemistry can be applied to develop novel artificial aldolases, and chemo- and
biocatalysis can be combined for the efficient synthesis of organic chemicals for industrial …

… to further error prone PCR produced an enzyme with activity approaching that of a
natural aldolase, notable for an artificial enzyme. This work demonstrates how powerful the …

… approach towards the design of artificial aldolase mimics. … As implied in the title of the thesis,
the artificial enzymes … , previous methods used in artificial aldolases will be exemplified. A …

… aldolase enzymes, aldolase ribozymes, or synthetic peptides and foldamers with aldolase
activity, outlining first steps toward … design biologically compatible artificial catalysts that mimic …

… advanced artificial enzyme by polymeric modularity as an efficient aldolase mimic for aqueous
asymmetric aldol reactions. Based on an in-depth understanding of the aldolase reaction …

… Here we show that an artificial aldolase with high specificity … attempts to redesign natural
aldolases, suggesting that such … , but engineering of natural aldolases to meet synthetic needs …

… to generate artificial enzymes by … artificial polyenzymes, abbreviated as “ArPoly”, have similar
physicochemical properties as natural enzymes and proved to be effective aldolase mimics …

… Both enzymes families were initially classified as glycine-dependent aldolases, owing to
their strict selectivity towards this amino acid as a nucleophile. Through classical screening, two …