Toxicology ontology perspectives

B Hardy, G Apic, P Carthew, D Clark, D Cook… - ALTEX-Alternatives to …, 2012 - altex.org
… , in vitro, and in vivo toxicology methods and related analysis and … ontology developments
based on a set of perspectives showing how ontologies are being used in predictive toxicology

Ontology-based data integration for advancing toxicological knowledge

RR Boyles, AE Thessen, A Waldrop… - … Opinion in Toxicology, 2019 - Elsevier
… of ontologies and present our vision for computationally enabled semantic toxicology. …
Ultimately, we argue that the large-scale adoption of ontologies across the field will help translate …

Current status and future perspective of computational toxicology in drug safety assessment under ontological intellection

Y Yamagata, H Yamada, I Horii - The Journal of Toxicological …, 2019 - jstage.jst.go.jp
… A pharmaceutical safety evaluator as a related toxicologist … thinking based on philosophical
ontology theory is necessary for … and future perspective of computational toxicology related to …

Ontology-based semantic mapping of chemical toxicities

RL Wang, S Edwards, C Ives - Toxicology, 2019 - Elsevier
… a new perspective of semantically similar … toxicological applications of OS-Mapping by
converting previously published toxicity responses to chemicals into CSPPs of multiple ontology

Ontological approach to the knowledge systematization of a toxic process and toxic course representation framework for early drug risk management

Y Yamagata, H Yamada - Scientific Reports, 2020 - nature.com
… Our approach is hence able to transfer knowledge between toxicology and clinical
medicine through commonalities. Therefore, from the perspectives of both toxicity and disease, …

[PDF][PDF] Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base

M Waters - Environmental Health Perspectives, 2003 - ehp.niehs.nih.gov
… treatment-related gene and protein expression profiles, and determining the relationships
of these gene/protein groups to functional pathways, we will consult gene ontology from the …

New perspectives in toxicological information management, and the role of ISSTOX databases in assessing chemical mutagenicity and carcinogenicity

R Benigni, CL Battistelli, C Bossa… - …, 2013 - academic.oup.com
Toxicological Ontology, which—at present—is lacking. A first phase of the project was
concluded in 2012 and has generated ontologies for three toxicological … of the ontology project is …

Proteomics in systems toxicology

C Madeira, PM Costa - Advances in protein chemistry and structural biology, 2021 - Elsevier
… , they offer a more realistic perspective of toxicopathic effects, … Toxicologists have long
focused on proteins as biomarkers … Gene ontology (GO) associates biological functions to …

Progress in data interoperability to support computational toxicology and chemical safety evaluation

S Watford, S Edwards, M Angrish, RS Judson… - Toxicology and applied …, 2019 - Elsevier
… a number of toxicology-related efforts specifically related to bioactivity and toxicological data
… of NAM and traditional toxicology information to support data-driven toxicology applications. …

Information extraction in the life sciences: perspectives for medicinal chemistry, pharmacology and toxicology

M Zimmermann, J Fluck, LT Thi… - Current Topics in …, 2005 - ingentaconnect.com
… , pharmacology and toxicology are descriptive sciences. … of pharmacology, medicinal
chemistry and toxicology. Finally, we will … , pharmacology and toxicology by linking information on …