Tissue repair responses in metazoans are highly coordinated by different cell types over
space and time. However, comprehensive single-cell-based characterization covering this
coordination is lacking. Here, we captured transcriptional states of single cells over space
and time during skin wound closure, revealing choreographed gene-expression profiles. We
identified shared space-time patterns of cellular and gene program enrichment, which we
call multicellular" movements" spanning multiple cell types. We validated some of the …