Transdermal fentanyl: an overview of pharmacokinetics, efficacy and safety
M Southam, S Gupta, M Knowles, SS Hwang - Transdermal Fentanyl: A …, 1991 - Springer
M Southam, S Gupta, M Knowles, SS Hwang
Transdermal Fentanyl: A New Approach to Prolonged Pain Control, 1991•SpringerAbstract The development of Transdermal Therapeutic System (Fentanyl)(TTS fentanyl) has
combined fentanyl, an opioid that has been used for over 20 years, with a transdermal drug
delivery system [Alza Corporation, Palo Alto, CA]. The system controls release of fentanyl to
maintain a continuous and steady supply of drug through the skin. Application of a new TTS
fentanyl every 72 h can provide the sustained and relatively constant serum fentanyl
concentrations associated with continuous intravenous or subcutaneous opioid delivery but …
combined fentanyl, an opioid that has been used for over 20 years, with a transdermal drug
delivery system [Alza Corporation, Palo Alto, CA]. The system controls release of fentanyl to
maintain a continuous and steady supply of drug through the skin. Application of a new TTS
fentanyl every 72 h can provide the sustained and relatively constant serum fentanyl
concentrations associated with continuous intravenous or subcutaneous opioid delivery but …
Abstract
The development of Transdermal Therapeutic System (Fentanyl) (TTS fentanyl) has combined fentanyl, an opioid that has been used for over 20 years, with a transdermal drug delivery system [Alza Corporation, Palo Alto, CA]. The system controls release of fentanyl to maintain a continuous and steady supply of drug through the skin. Application of a new TTS fentanyl every 72 h can provide the sustained and relatively constant serum fentanyl concentrations associated with continuous intravenous or subcutaneous opioid delivery but without invasive procedures or special equipment.
Springer
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