Transfer of bisphenol A across the human placenta

B Balakrishnan, K Henare, EB Thorstensen… - American journal of …, 2010 - Elsevier
… a rapid maternofetal transfer of BPA across the human placenta. The transfer percentage
and … Our results thus imply that BPA freely diffuses across the human placenta at a rate that is …

Is bisphenol S a safer alternative to bisphenol A in terms of potential fetal exposure? Placental transfer across the perfused human placenta

FC Grandin, MZ Lacroix, V Gayrard, C Viguié, H Mila… - Chemosphere, 2019 - Elsevier
The aim of our study was to evaluate the bidirectional transfer of Bisphenol S (BPS) and its
main metabolite, BPS Glucuronide (BPSG), using the model of perfused human placenta and …

Bidirectional placental transfer of Bisphenol A and its main metabolite, Bisphenol A-Glucuronide, in the isolated perfused human placenta

T Corbel, V Gayrard, S Puel, MZ Lacroix, A Berrebi… - Reproductive …, 2014 - Elsevier
… The present study uses the isolated perfused human placenta to examine the placental
transport of BPA and its main metabolite, BPA-G in humans. Antipyrine, a reference marker for …

Comparison of the materno-fetal transfer of fifteen structurally related bisphenol analogues using an ex vivo human placental perfusion model

CA Gély, MZ Lacroix, M Morin, C Vayssière, V Gayrard… - Chemosphere, 2021 - Elsevier
… the placenta is therefore crucial to assess prenatal exposure … the placental transfer of a set
of 15 selected bisphenols (BPs) … BPZ) using the ex vivo human placental perfusion model. The …

Placental transport and in vitro effects of Bisphenol A

TJ Mørck, G Sorda, N Bechi, BS Rasmussen… - Reproductive …, 2010 - Elsevier
… To identify toxic concentrations of BPA in human placenta, we analyzed cell viability and
β-hCG secretion in a test range of 10 pM to 1 mM using BeWo cells. We found that BPA …

Placental transfer of conjugated bisphenol A and subsequent reactivation in the rat fetus

M Nishikawa, H Iwano, R Yanagisawa… - Environmental …, 2010 - ehp.niehs.nih.gov
… metabolite—is passed through the placenta to the fetus, where it affects the fetus after
reactivation, we investigated the placental transfer of BPA-GA and reactivation to BPA in the fetus. …

[HTML][HTML] Prenatal nutrition containing bisphenol A affects placenta glucose transfer: evidence in rats and human trophoblast

L Benincasa, M Mandalà, L Paulesu, L Barberio, F Ietta - Nutrients, 2020 - mdpi.com
… The transfer of glucose across the human placenta is one-way … Glucose crosses placental
membranes through a family of … to be the primary placental transporter of glucose from the …

… and maternal transfer of multiple bisphenols, including an emerging derivative with unexpectedly high concentrations, in the human maternal–fetal–placental unit

Y Pan, M Deng, J Li, B Du, S Lan… - … science & technology, 2020 - ACS Publications
… the main mechanism of placental transfer because it was affected … human placenta remains
unexamined, but this study provided the first evidence that BPS passes through the placenta

Bisphenol A disrupts gene expression in human placental trophoblast cells

C Rajakumar, H Guan, D Langlois, M Cernea… - Reproductive …, 2015 - Elsevier
… effect of bisphenol A (BPA) on human placental gene expression using primary trophoblast
cells as an in vitro model system. Trophoblast cells were isolated from human placentas at …

The impact of bisphenol A on the placenta

EA Adu-Gyamfi, CS Rosenfeld… - Biology of …, 2022 - academic.oup.com
placenta architecture and a diagram of the major cell types in mouse and human placenta, …
Although these models do not fully mirror in vivo human placental conditions, their use is …