Since the advent of technologies to produce genetic knockout and transgenic mice, the
number of mouse strains suggested to be useful as models for pregnancy-related
complications in the human has risen substantially. Some of these share features in
common with fetal growth restriction (FGR) and preeclampsia (PE) and could be useful for
investigating aetiologies and for testing potential therapeutics to improve outcome in these
diseases. However, since placental pathology is a major underlying factor in both FGR and …