Treatment of muscle invasive bladder cancer in the elderly: navigating the trade-offs of risk and benefit
NA VanderWalde, MT Chi, A Hurria, MD Galsky… - World journal of …, 2016 - Springer
NA VanderWalde, MT Chi, A Hurria, MD Galsky, ME Nielsen
World journal of urology, 2016•SpringerPurpose Despite the fact that bladder cancer patients have the highest median age of any
type of cancer, older patients with muscle invasion are often under-treated. Methods In this
review, we report the most up to date literature on the patterns of care and treatment of older
patients with muscle invasive bladder cancer. Data on under-treatment, geriatric principles,
cystectomy, perioperative chemotherapy, and bladder preservation for older patients are
presented and analyzed. Conclusion Chronologic age should not exclude patients from …
type of cancer, older patients with muscle invasion are often under-treated. Methods In this
review, we report the most up to date literature on the patterns of care and treatment of older
patients with muscle invasive bladder cancer. Data on under-treatment, geriatric principles,
cystectomy, perioperative chemotherapy, and bladder preservation for older patients are
presented and analyzed. Conclusion Chronologic age should not exclude patients from …
Purpose
Despite the fact that bladder cancer patients have the highest median age of any type of cancer, older patients with muscle invasion are often under-treated.
Methods
In this review, we report the most up to date literature on the patterns of care and treatment of older patients with muscle invasive bladder cancer. Data on under-treatment, geriatric principles, cystectomy, perioperative chemotherapy, and bladder preservation for older patients are presented and analyzed.
Conclusion
Chronologic age should not exclude patients from curative-intent therapy. Functional age as determined by geriatric assessments and multidisciplinary evaluation can help clinicians decide on the best course of treatment for individual patients. Cystectomy, perioperative chemotherapy, and curative-intent bladder preservation are reasonable options in healthy older adults. Observation should be limited to patients with extremely poor performance status and very limited life expectancy.
Springer
以上显示的是最相近的搜索结果。 查看全部搜索结果