[引用][C] Treatment of severe post-traumatic bruxism with botulinum toxin-A: case report

FS Pidcock, JM Wise, JR Christensen - Journal of oral and maxillofacial …, 2002 - joms.org
Discussion Botulinum toxin-A is a neurotoxin produced by the bacterium Clostridium
botulinum. It blocks the release of acetylcholine at neuromuscular junctions by temporarily
inactivating the protein synaptosomal-associated protein-25. 5 Weakness of the targeted
muscles occurs, usually lasting between 1 and 6 months. In the other case reports, where
botulinum toxin was used to post-traumatic bruxism, 1 or 2 treatment sessions were
required. 3, 4 Persistence of the effect after treatment is most likely related to improvements …
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