Triazole Fungicides Can Induce Cross-Resistance to Medical Triazoles in Aspergillus fumigatus

E Snelders, SMT Camps, A Karawajczyk… - PloS one, 2012 - journals.plos.org
could have been fungicide driven. Our hypothesis was that cross-resistance could develop if
DMIs and medical triazoles … 34 /L98H substitutions could be induced through DMI-exposure …

Evolution of cross-resistance to medical triazoles in Aspergillus fumigatus through selection pressure of environmental fungicides

J Zhang, J van den Heuvel… - … of the Royal …, 2017 - royalsocietypublishing.org
… confirmed that these SI fungicides can induce cross-resistance to medical triazoles. Thus, …
Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus. …

Aspergillus fumigatus cross-resistance between clinical and demethylase inhibitor azole drugs

R Garcia-Rubio, I Gonzalez-Jimenez… - Applied and …, 2021 - Am Soc Microbiol
… of clinical triazoles and demethylation inhibitor compounds used in this study, grouped as
imidazole or triazole fungicidesTriazole fungicides can induce cross-resistance to medical

Mechanisms of triazole resistance in Aspergillus fumigatus

AV Nywening, JM Rybak, PD Rogers… - Environmental …, 2020 - Wiley Online Library
… with clinical and environmental resistance to triazoles in A. … with cross-resistance to multiple
triazole compounds including … potential contributor to triazole antifungal resistance is beyond …

[HTML][HTML] Triazole resistance in Aspergillus fumigatus: recent insights and challenges for patient management

PPA Lestrade, JF Meis, WJG Melchers… - Clinical Microbiology and …, 2019 - Elsevier
… infrequent cause of infection in most geographic regions [3]. … for fungicide application, but
many triazole fungicides where … with triazoles, isolates may emerge with aberrant triazole

Characterization of Aspergillus fumigatus cross-resistance between clinical and DMI azole drugs.

R Garcia-Rubio, I Gonzalez-Jimenez… - Applied and …, 2020 - europepmc.org
… of clinical triazoles and demethylation inhibitor compounds used in this study, grouped as
imidazole or triazole fungicidesTriazole fungicides can induce cross-resistance to medical

Triazole resistance surveillance in Aspergillus fumigatus

, … Aspergillus Resistance Surveillance Working … - Medical …, 2018 - academic.oup.com
… studies and stimulate international collaborations. Important … fungicides of the triazole class,
which are molecularly similar to medical triazoles and to whom cross-resistance with medical

Fungicide effects on human fungal pathogens: cross-resistance to medical drugs and beyond

RW Bastos, L Rossato, GH Goldman… - PLoS Pathogens, 2021 - journals.plos.org
… We also examine data showing that fungicide exposure can select relevant changes in the
Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus

Anti-fungal activity of a novel triazole, PC1244, against emerging azole-resistant Aspergillus fumigatus and other species of Aspergillus

T Colley, C Sharma, A Alanio, G Kimura… - Journal of …, 2019 - academic.oup.com
… systemic antifungal treatment. Here we report antifungal activities of a novel inhaled triazole,
fumigatus was identified as the cause of the resistance phenotype to voriconazole 22 , 23 …

Development of cross-resistance by Aspergillus fumigatus to clinical azoles following exposure to prochloraz, an agricultural azole

I Faria-Ramos, S Farinha, J Neves-Maia, PR Tavares… - BMC microbiology, 2014 - Springer
… Our study demonstrated the time frame between the introduction of a widely used agricultural
antifungal and the emergence of cross-resistance to medical triazoles. During the induction