Circulating tumor cells (CTCs) have shown potential for cancer diagnosis and prognosis.
Affinity-based CTC isolation methods have been proved to be efficient for CTC detection in
clinical blood samples. One of the popular choices for affinity-based CTC isolation is to
immobilize capture agents onto an array of microposts in microchannels, providing high
CTC capture efficiency due to enhanced interactions between tumor cells and capture
agents on the microposts. However, how the cells interact with microposts under different …