Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
C Chang, SL Banerjee, SS Park, XL Zhang… - Elife, 2024 - elifesciences.org
Eph receptor tyrosine kinases participate in a variety of normal and pathogenic processes
during development and throughout adulthood. This versatility is likely facilitated by the
ability of Eph receptors to signal through diverse cellular signalling pathways: primarily by
controlling cytoskeletal dynamics, but also by regulating cellular growth, proliferation, and
survival. Despite many proteins linked to these signalling pathways interacting with Eph
receptors, the specific mechanisms behind such links and their coordination remain to be …
during development and throughout adulthood. This versatility is likely facilitated by the
ability of Eph receptors to signal through diverse cellular signalling pathways: primarily by
controlling cytoskeletal dynamics, but also by regulating cellular growth, proliferation, and
survival. Despite many proteins linked to these signalling pathways interacting with Eph
receptors, the specific mechanisms behind such links and their coordination remain to be …
[HTML][HTML] Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
C Chang, SL Banerjee, SS Park, X Zhang… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Eph receptor tyrosine kinases participate in a variety of normal and pathogenic processes
during development and throughout adulthood. This versatility is likely facilitated by the
ability of Eph receptors to signal through diverse cellular signalling pathways: primarily by
controlling cytoskeletal dynamics, but also by regulating cellular growth, proliferation, and
survival. Despite many proteins linked to these signalling pathways interacting with Eph
receptors, the specific mechanisms behind such links and their coordination remain to be …
during development and throughout adulthood. This versatility is likely facilitated by the
ability of Eph receptors to signal through diverse cellular signalling pathways: primarily by
controlling cytoskeletal dynamics, but also by regulating cellular growth, proliferation, and
survival. Despite many proteins linked to these signalling pathways interacting with Eph
receptors, the specific mechanisms behind such links and their coordination remain to be …
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