The Next Generation Space Telescope (NGST) Project is developing a new generation of near-infrared (NIR; λ=0.6-5 μm) array detectors optimized for ultra-low space-based backgrounds. NASA has selected the Independent Detector Testing Laboratory (IDTL) at the Space Telescope Science Institute (STScI) and the Johns Hopkins University to assist in testing and characterizing NGST's near-infrared detectors. In the IDTL, we have begun to explore how reference pixels might be used to calibrate infrared array data. Here we report some early results from these studies. Results to date are very encouraging, particularly with regard to techniques using temporal or spatial averaging to compute low-noise reference levels before making row-by-row reference pixel corrections. We explored the effectiveness of four potential calibration strategies using a shorting resistor installed where the detector would normally mount and are currently validating the techniques presented here using candidate NGST detectors.