Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants

L Wang, T Zhou, Y Zhang, ES Yang, CA Schramm… - Science, 2021 - science.org
… To gain structural insights on the interaction between this class of antibodies and the
SARS-CoV-2 spike, we obtained cryo–electron microscopy (cryo-EM) reconstructions for structures …

[HTML][HTML] Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants

L Wang, T Zhou, Y Zhang, ES Yang, CA Schramm… - BioRxiv, 2021 - ncbi.nlm.nih.gov
… between this class of antibodies and the SARS-CoV-2 spike, we mixed A23–… Ultrapotent
antibodies from convalescent donors neutralize and mitigate resistance of SARS-CoV-2 variants

A subset of Memory B-derived antibody repertoire from 3-dose vaccinees is ultrapotent against diverse and highly transmissible SARS-CoV-2 variants, including …

K Wang, Z Jia, L Bao, L Wang, L Cao, H Chi, Y Hu, Q Li… - BioRxiv, 2021 - biorxiv.org
SARS-CoV-2. None of the volunteers recruited for vaccination was infected by SARS-CoV-2
study, to compare NAb titers against circulating SARS-CoV-2 variants. An early passage of …

Extremely potent monoclonal antibodies neutralize Omicron and other SARS-CoV-2 variants

Z Chen, P Zhang, Y Matsuoka, Y Tsybovsky, K West… - MedRxiv, 2022 - medrxiv.org
… the SARS-CoV-2 spike protein with ultrapotent neutralizing … -19 patients with high titers
of neutralizing antibodies. Here, we … neutralize diverse and highly transmissible SARS-CoV-2

Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants

T Ozawa, H Tani, Y Anraku, S Kita, E Igarashi, Y Saga… - MAbs, 2022 - Taylor & Francis
… (ACE2) expressed on cells in various tissues, such as lung and the … a highly potent neutralizing
antibody against SARS-CoV-2 VOCs, … The viral infectious dose of each supernatant was …

[PDF][PDF] Ultrapotent antibodies against diverse and highly

L Wangºf, T Zhou, Y Zhang, ES Yang, CA Schramm… - scienceopen.com
highly transmissible SARS-CoV-2 variants of concern (VOC) that are resistant to therapeutic
antibodies … between this class Of antibodies and the SARS-CoV-2 spike, we obtained cryo-…

[HTML][HTML] Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants

K Wang, Z Jia, L Bao, L Wang, L Cao, H Chi, Y Hu, Q Li… - Nature, 2022 - nature.com
very similar to A23-58.1, an ultrapotent and broadly reactive neutralizing antibody effective
against 23 SARS-CoV-2 variants … documented in some other infectious diseases, including flu …

[HTML][HTML] Broadly neutralizing antibodies to SARS-CoV-2 provide novel insights into the neutralization of variants and other human coronaviruses

P Bajpai, V Singh, A Chandele… - … in cellular and infection …, 2022 - frontiersin.org
… The recently emerged, highly mutated, and transmissible … Shannon entropy, is a measure
of diversity and hence … be effective to combat highly mutated SARS-CoV-2 variants and any …

[PDF][PDF] Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B. 1.1. 7 variant

C Graham, J Seow, I Huettner, H Khan, N Kouphou… - Immunity, 2021 - cell.com
… in neutralization potency against the recently reported highly transmissible B.1.1.7 variant of
… nAb responses following SARS-CoV-2 infection differ between donors with varied COVID-…

Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

JL Torres, G Ozorowski, E Andreano… - Proceedings of the …, 2022 - National Acad Sciences
… was able to neutralize all SARS-CoV-2 variants but in the 4- to 41-… Two different approaches
were used to evaluate the … solution containing 100 median tissue culture infectious dose (…