There is an increasing trend for designers to use living systems, through biodesign and biophilia in the urban environment. As new creative processes emerge, the perception and emotional responses of users towards these new systems are somewhat unknown. This paper aims to study the emotional responses and perceptions towards biological materials that are embedded in existing product designs. Data was collected from 58 respondents through an online questionnaire. The findings from this exploratory study show that the significant differences by comparing the respondents with a background in design and non-design towards the level of desirability, practicality, aesthetically pleasing and the common use towards artificial and real biological materials. This paper extends existing understanding of perception and emotional responses to design incorporated living systems and can begin validating existing studies which have brought different perspectives towards the functions, practicality, aesthetical value and emotional attachments of products.