Urinary-cell mRNA profile and acute cellular rejection in kidney allografts
M Suthanthiran, JE Schwartz, R Ding… - New England journal …, 2013 - Mass Medical Soc
Background The standard test for the diagnosis of acute rejection in kidney transplants is the
renal biopsy. Noninvasive tests would be preferable. Methods We prospectively collected
4300 urine specimens from 485 kidney-graft recipients from day 3 through month 12 after
transplantation. Messenger RNA (mRNA) levels were measured in urinary cells and
correlated with allograft-rejection status with the use of logistic regression. Results A three-
gene signature of 18S ribosomal (rRNA)–normalized measures of CD3ε mRNA and …
renal biopsy. Noninvasive tests would be preferable. Methods We prospectively collected
4300 urine specimens from 485 kidney-graft recipients from day 3 through month 12 after
transplantation. Messenger RNA (mRNA) levels were measured in urinary cells and
correlated with allograft-rejection status with the use of logistic regression. Results A three-
gene signature of 18S ribosomal (rRNA)–normalized measures of CD3ε mRNA and …
[引用][C] Urinary-cell mRNA profile and acute cellular rejection in kidney allografts.
DA Goldfarb - The Journal of Urology, 2013 - europepmc.org
Urinary-cell mRNA profile and acute cellular rejection in kidney allografts. - Abstract -
Europe PMC … Urinary-cell mRNA profile and acute cellular rejection in kidney allografts. …
This is a comment on "Urinary-cell mRNA profile and acute cellular rejection in kidney
allografts." N Engl J Med. 2013 Jul 4;369(1):20-31. …
Europe PMC … Urinary-cell mRNA profile and acute cellular rejection in kidney allografts. …
This is a comment on "Urinary-cell mRNA profile and acute cellular rejection in kidney
allografts." N Engl J Med. 2013 Jul 4;369(1):20-31. …
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