Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide.
Non-coding RNAs have already been linked to CVD development and progression. While
microRNAs (miRs) have been well studied in blood samples, there is little data on tissue-
specific miRs in cardiovascular relevant tissues and their relation to cardiovascular risk
factors. Tissue-specific miRs derived from Arteria mammaria interna (IMA) from 192 coronary
artery disease (CAD) patients undergoing coronary artery bypass grafting (CABG) were …

… The aims of the study were 1) to establish a reference atlas which can be utilized for
identification of novel diagnostic biomarkers and potential therapeutic targets, and 2) to
relate these miRs to cardiovascular risk factors. Methods: Overall, 393 individual miRs
showed sufficient expression levels and passed quality control for further analysis. …
Results: We identified 17 miRs–miR-10b-3p, miR-10-5p, miR-17-3p, miR-21-5p, miR-151a-5p,
miR-181a-5p, miR-185-5p, miR-194-5p, miR-199a-3p, miR-199b-3p, miR-212-3p, miR-363-3p …