Verification of p-glycoprotein function at the dermal barrier in diffusion cells and dynamic “skin-on-a-chip” microfluidic device
The efficacy of transdermal absorption of drugs and the irritation or corrosion potential of
topically applied formulations are important areas of investigation in pharmaceutical, military
and cosmetic research. The aim of the present experiments is to test the role of P-
glycoprotein in dermal drug delivery in various ex vivo and in vitro platforms, including a
novel microchip technology developed by Pázmány Péter Catholic University. A further
question is whether the freezing of excised skin and age have any influence on P …
topically applied formulations are important areas of investigation in pharmaceutical, military
and cosmetic research. The aim of the present experiments is to test the role of P-
glycoprotein in dermal drug delivery in various ex vivo and in vitro platforms, including a
novel microchip technology developed by Pázmány Péter Catholic University. A further
question is whether the freezing of excised skin and age have any influence on P …
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