Radial modulation imaging is a contrast agent-specific imaging approach for improving
microbubble detection at high imaging frequencies (≥ 7.5 MHz), with imaging depth limited
to a few centimeters. To provide high-sensitivity contrast-enhanced ultrasound imaging at
high penetration depths, a new radial modulation imaging strategy using a very low
frequency (100 kHz) ultrasound modulation wave in combination with imaging pulses≤ 5 …