Vgll3 and the Hippo pathway are regulated in Sertoli cells upon entry and during puberty in Atlantic salmon testis

E Kjærner-Semb, F Ayllon, L Kleppe, E Sørhus… - Scientific Reports, 2018 - nature.com
Vgll3 is linked to age at maturity in Atlantic salmon (Salmo salar). However, the molecular
mechanisms involving Vgll3 in controlling timing of puberty as well as relevant tissue and
cell types are currently unknown. Vgll3 and the associated Hippo pathway has been linked
to reduced proliferation activity in different tissues. Analysis of gene expression reveals for
the first time that vgll3 and several members of the Hippo pathway were down-regulated in
salmon testis during onset of puberty and remained repressed in maturing testis. In the …

[引用][C] Vgll3 and the Hippo pathway are regulated in Sertoli cells upon entry and during puberty in Atlantic salmon testis, Sci Rep 8: 1912

E Kjærner-Semb, F Ayllon, L Kleppe, E Sørhus… - 2018
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