Vitamin D, cytokine profiles, and disease severity in infants with atopic dermatitis: a single centre, cross-sectional study
W Barlianto, D Wulandari, T Sari, V Firdayanti… - … in Dermatology and …, 2022 - termedia.pl
W Barlianto, D Wulandari, T Sari, V Firdayanti, M Avandi
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 2022•termedia.pl… Interleukin (IL)-17, which is produced mainly by Th17, was considered to serve as an
initial cytokine source for the development of inflammatory responses in AD [18]. A study
reported that vitamin D supplementation in patients with AD leads to a decrease in the
number of CD4 T-cells producing IL-17 and improves the disease severity [19]. Th22 has
also been identified as those that play a role in pathogenesis of AD, however limited data
were available [20, 21]. There is an ongoing need to investigate the role of vitamin D on …
initial cytokine source for the development of inflammatory responses in AD [18]. A study
reported that vitamin D supplementation in patients with AD leads to a decrease in the
number of CD4 T-cells producing IL-17 and improves the disease severity [19]. Th22 has
also been identified as those that play a role in pathogenesis of AD, however limited data
were available [20, 21]. There is an ongoing need to investigate the role of vitamin D on …
Aim
The aim of the study was to evaluate the correlation between 25 (OH) D and immune profiles (IL-4, IL-17, and IL-22 cytokines, eosinophil count, tIgE serum levels) and also SCORAD index in infants with AD.
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