necrotizing granulomatous lesions of the upper and lower respiratory tracts and a
generalized vasculitis of small to medium-sized vessels, often associated with a
glomerulonephritis [4]. Kidney involvement is common, but extrarenal manifestations usually
precede renal disease by many months [5, 6]. Renal pathology usually reveals a focal
segmental necrotizing glomerulonephritis, with or without crescents, and rarely …
M Frigui,
MB Hmida, M Kechaou, R Jlidi… - Rheumatology …, 2009 - Springer
Wegener's granulomatosis (WG) is a disease of unknown etiology characterized by
necrotizing granulomatous vascularitis. The upper and lower respiratory tract and kidney
involvements are very common; however, its presentation as bilateral renal masses is
unusual. We report a case of a 59-year-old female patient who presented with multiple
bilateral renal masses. The patient presented with sinusal and ocular symptoms suggestive
of WG, and positive antineutrophil cytoplasmic antibodies (c-ANCA) with an anti-PR3 …