Whole genome sequencing of toxigenic Clostridium difficile in asymptomatic carriers: insights into possible role in transmission

FD Halstead, A Ravi, N Thomson, M Nuur… - Journal of Hospital …, 2019 - Elsevier
Background Estimates of the prevalence of asymptomatically carried Clostridium difficile in
elderly patients in long-term care range from 0% to 51%. Asymptomatic carriage is possibly
a risk factor for the development of infection, and there is ongoing debate surrounding the
role of asymptomatic carriage in transmission. Aim To investigate the prevalence of
asymptomatic carriage amongst patients residing in intermediate care (bedded) facilities
(ICBFs), and to investigate whether asymptomatically carried C. difficile strains contribute to …
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