Xpert MTB/RIF Ultra assay for the diagnosis of pulmonary tuberculosis in children: a multicentre comparative accuracy study
Objectives We evaluated the diagnostic performance of the novel next-generation Xpert
MTB/RIF Ultra (Xpert Ultra) in comparison to Xpert MTB/RIF (Xpert) assay for the detection of
paediatric pulmonary tuberculosis in high burden settings. Methods From May 2011 to
September 2012, children with suspected pulmonary tuberculosis were enrolled at two
Tanzanian sites and sputum samples were examined using sputum smear, Xpert and
culture. Xpert Ultra was tested between January and June 2017 using sputum pellets, which …
MTB/RIF Ultra (Xpert Ultra) in comparison to Xpert MTB/RIF (Xpert) assay for the detection of
paediatric pulmonary tuberculosis in high burden settings. Methods From May 2011 to
September 2012, children with suspected pulmonary tuberculosis were enrolled at two
Tanzanian sites and sputum samples were examined using sputum smear, Xpert and
culture. Xpert Ultra was tested between January and June 2017 using sputum pellets, which …
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