… Over the past decade, genome-wide association studies (GWAS) have … of kidney function
and disease. Population-based studies, used to investigate traits that define chronic kidney …

Chronic kidney disease (CKD) is common, affecting about 10% of the general population,
and causing significant morbidity and mortality. Apart from the risk conferred by traditional …

… -up studies stimulated by findings from genome-wide association studies of kidney disease
are already yielding promising results, such as the identification of an association between …

… Using 280 kidney … of kidney disease) and observe increased renal expression of a specific
MUC1 mRNA isoform as a plausible molecular mechanism of the GWAS association signal. …

… to kidney disease is supported by heritability studies of kidney function measures, the presence
of monogenic diseases with … studies of complex kidney diseases, such as chronic kidney …

… renal disease (ESRD). Hence, modifying factors likely contribute to initiation of kidney disease
… In this report, genome-wide association studies and a meta-analysis were performed to …

… Exome capture and next generation sequencing techniques, together with advances in
bioinformatics, have led to epigenome-wide association studies and the promise of more …

… Thus, our study confirms some of the previously reported kidney disease associated CpGs
including ANKRD11 at epigenome-wide significance, while discovering and replicating 18 …

… association studies (GWAS) can uncover the genetic underpinnings of complex human traits
and diseases. … of known risk loci for genetic kidney diseases. Rare mutations in SLC7A9, …

… We conducted genome-wide association studies (GWAS) to identify susceptibility loci for
glomerular filtration rate, estimated by serum creatinine (eGFRcrea) and cystatin C (eGFRcys), …