[HTML][HTML] A single-cell atlas of the tumor and immune ecosystem of human breast cancer

J Wagner, MA Rapsomaniki, S Chevrier, T Anzeneder… - Cell, 2019 - cell.com
… of breast cancer ecosystems. Tumor ecosystems are comprised of cancer cells, infiltrating
immune cells, stromal cells, and other cell types together with non-cellular tissue components ( …

Breast cancers as ecosystems: a metabolic perspective

F Martino, M Lupi, E Giraudo, L Lanzetti - Cellular and Molecular Life …, 2023 - Springer
… occurring in the cancer cell. In adopting this perspective, a metabolic vision of the cancer
ecosystem is bound to improve our understanding of the natural history of cancer, across space …

An ecological measure of immune-cancer colocalization as a prognostic factor for breast cancer

CC Maley, K Koelble, R Natrajan, A Aktipis… - Breast Cancer …, 2015 - Springer
… We applied ecological measures of species interactions to digital pathology images … immune
and cancer cells in breast cancer. We used the Morisita-Horn similarity index, an ecological

Unveiling the Complex Ecosystem of Breast Cancer: Crucial Insights for Patients and Doctors

K Mokbel - Anticancer Research, 2024 - ar.iiarjournals.org
… Notably, treatments like immunotherapy and radiation therapy stimulate immune responses
against breast cancer, potentially reducing the risk of distant metastasis. However, the …

Single-cell morphological and topological atlas reveals the ecosystem diversity of human breast cancer

S Zhao, DP Chen, T Fu, JC Yang, D Ma, XZ Zhu… - Nature …, 2023 - nature.com
… Tumors are increasingly recognized as an “ecosystem” composed of tumor, immune and …
Based on the sc-MTOP data, we aimed to dissect the diversity of breast cancer ecosystem at …

The balance between breast cancer and the immune system: Challenges for prognosis and clinical benefit from immunotherapies

CN Baxevanis, SP Fortis, SA Perez - Seminars in cancer biology, 2021 - Elsevier
… mostly via genetic and epigenetic modifications which have a destructive impact on the
human ecosystem and also protect tumor cells from immune attack and help them to escape from …

The theory of tumor ecosystem

X Chen, E Song - Cancer Communications, 2022 - Wiley Online Library
… cells and their local microenvironment, distant organ niches, immune, … breast cancer as an
example, the patient's systemic environment can be perceived as an integral ecosystem and …

From immunohistochemistry to new digital ecosystems: a state-of-the-art biomarker review for precision breast cancer medicine

SM Hacking, E Yakirevich, Y Wang - Cancers, 2022 - mdpi.com
… The immune infiltrate … immune response against the tumor. In recent years, with the increased
interest in tumor immunotherapy and the intense investigation of the breast cancer immune

[HTML][HTML] Subverted macrophages in the triple-negative breast cancer ecosystem

L Shang, Y Zhong, Y Yao, C Liu, L Wang… - Biomedicine & …, 2023 - Elsevier
… the entire immune ecosystem, and thus have an overriding effect [28]. Reprogramming
should be performed according to the functions of TAMs to restore the immune surveillance role …

Leveraging the dynamic immune environment triad in patients with breast cancer: tumour, lymph node, and peripheral blood

I Wall, V Boulat, A Shah, KRM Blenman, Y Wu… - Cancers, 2022 - mdpi.com
immune environment triad of breast cancer. It is critical that future studies seek to establish
dynamic immune … capture the systemic immune response to breast cancer and define patient-…