… In this report, we extend the kidney development atlas to single cell resolution. At several …
of cells that will contribute to the stromal, nephron and vascular components of the kidney. …

… are important for kidney induction and subsequent development. Another caveat in these
rat experiments is the use of isolated mesenchyme that has been dissected free from ureteric …

… Herein, using cell sorting, RNA sequencing, in vitro studies … kidney development and
tumorigenesis; In nephrogenesis, NCAM1 + CD133 − marks SIX2 + multipotent renal stem cells …

… fetal kidneys remains limited. To address the key features of human fetal kidney development,
we applied single-cell RNA sequencing (scRNA-seq) to >3,000 renal cells spanning …

… pression profiles of the major elements of kidney development. This data set represents the
… .5 and E15.5 kidneys (metanephroi) were rapidly dissected from embryos and stored briefly …

… In our original approach, we developed a ureteric bud-derived cell line [5] and assayed
fractions for their potential to induce epithelialization in metanephric mesenchyme. This led to the …

… the developing kidney. Here, we document expression of the adult stem cell marker Lgr5
in the developing kidney and assess the stem/progenitor identity of Lgr5 +ve cells via in vivo …

… Kidney development is notable for requiring distinct but … of cell origins, are enhancing
our understanding of kidney … loci for the development of new genetic tools to dissect these …

… Similar to other organs, such as teeth, liver, or pancreas, secondary induction is a
phenomenon that also controls kidney development. When Grobstein dissected mouse kidney …

… of kidney development in mutant embryos undergoes programmed cell death around E12.5. …
the time of dissection, exhibited normal development in culture (B). However, the Gdf11 −/− …