SARS-CoV-2 cell tropism and multiorgan infection

J Liu, Y Li, Q Liu, Q Yao, X Wang, H Zhang, R Chen… - Cell discovery, 2021 - nature.com
… + vascular endothelial cells (green) in the lung (i), trachea (ii), small intestine (iii), and kidney
(iv). e Schematic of SARS-CoV-2 multiorgan infection and cell tropism in the human body. …

SARS‐CoV‐2 cellular tropism and direct multiorgan failure in COVID‐19 patients: Bioinformatic predictions, experimental observations, and open questions

AA Valyaeva, AA Zharikova… - Cell Biology …, 2023 - Wiley Online Library
… the most recent findings regarding SARS-CoV-2 cellular tropism and the possible connection
between the early stages of infection and multiorgan failure in COVID-19. The SARS-CoV-…

Orthohantavirus pathogenesis and cell tropism

D Noack, M Goeijenbier, CBEM Reusken… - … cellular and infection …, 2020 - frontiersin.org
… While both syndromes develop following respiratory transmission and are associated with
multi-organ failure and high mortality rates, little is known about the mechanisms that result in …

Human cytomegalovirus cell tropism and pathogenesis

C Sinzger, G Jahn - Intervirology, 1996 - karger.com
… While the spread of HCMV by productively infected circulating endothelial cells provides a
good explanation for the observation of systemic multiorgan infections, dis semination of the …

Multiorgan and vascular tropism of SARS-CoV-2

C Hartard, A Chaqroun, N Settembre, G Gauchotte… - Viruses, 2022 - mdpi.com
… Although the respiratory tract is the main target of SARS-CoV-2, other tissues and organs
are permissive to the infection. In this report, we investigated this wide-spectrum tropism by …

Human cytomegalovirus cell tropism and host cell receptors

G Gerna, A Kabanova, D Lilleri - Vaccines, 2019 - mdpi.com
… In 2004, a locus in the HCMV genome was identified (see below), which appeared to be
essential for both infection of endothelial cells (endothelial cell-tropism) and leukocytes (leuko-…

Cytomegalovirus cell tropism

C Sinzger, M Digel, G Jahn - Human cytomegalovirus, 2008 - Springer
Infection of epithelial cells presumably contributes to interhost transmission. Infection of
endothelial cells and hematopoietic cells … dissemination and multiorgan involvement has already …

Cytomegalovirus (CMV) pneumonitis: cell tropism, inflammation, and immunity

L Fonseca Brito, W Brune, FR Stahl - International journal of molecular …, 2019 - mdpi.com
… HCMV infection of the respiratory tract leads to pneumonitis … MCMV) likewise exhibits a distinct
tropism for the lung and thus … MCMV cell tropism and localized inflammation after infection

Tissue tropism in parasitic diseases

S Silva Pereira, S Trindade, M De Niz… - Open …, 2019 - royalsocietypublishing.org
… Here, we discuss current knowledge of tissue tropism in Trypanosoma infections in … findings
from other parasitology fields where tissue tropism has been extensively investigated, and …

Multisystemic cellular tropism of SARS-CoV-2 in autopsies of COVID-19 patients

DWL Wong, BM Klinkhammer, S Djudjaj, S Villwock… - Cells, 2021 - mdpi.com
Multiorgan tropism of SARS-CoV-2 has previously been shown for … a “cellular and whole-body
tissue atlas” of organ tropism profile of … spread in virtually all cell types of infected organs. …