Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

R Channappanavar, S Perlman - Seminars in immunopathology, 2017 - Springer
… excessive and prolonged cytokine/chemokine response known as “cytokine storms,” which
… that “cytokine storms” and immunopathology can occur during pathogenic hCOV infections, …

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… These pathological features are very similar to those of SARS-CoV and MERS-CoV
infections, 30, 31 indicating that effective treatments for SARS and MERS may be suitable for …

An enlightening role for cytokine storm in coronavirus infection

Z Zhao, Y Wei, C Tao - Clinical Immunology, 2021 - Elsevier
… of cytokine storm in the context of coronavirus infection and also discussed about the
complicated interactions among the cytokine storm, … inspirations to SARS-CoV-2 therapeutics and …

Cytokine storm syndrome in coronavirus disease 2019: A narrative review

YM Gao, G Xu, B Wang, BC Liu - Journal of internal medicine, 2021 - Wiley Online Library
… and chemokine responses played an important role in the pathogenesis of CoV infection [10].
A retrospective study also found that compared with nonsevere patients, intensive care …

Cytokine Storm and its Implication in Coronavirus disease 2019 (COVID-19)

C Datta, A Bhattacharjee - Journal of …, 2020 - immunologyresearchjournal.com
COVID-19. In this review, we intended to describe how cytokine storm is associated with the
severity of COVID-… response due to cytokine storm during COVID-19 infection using several …

Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
… disease progression and death in coronavirus infections. Cytokine storm not only limits further
… induced by SARS-CoV-2 infection may further cause cytokine storms and pneumonia, and …

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

F Coperchini, L Chiovato, L Croce, F Magri… - Cytokine & growth factor …, 2020 - Elsevier
… Taken together, these data clearly indicate that, in SARS-CoV infection, ARDS is the
ultimate result of a cytokine storm. In this scenario, the release by immune effector cells of large …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… -CoV-2 infection causes the cytokine storm… -CoV-2 and the mechanisms by which cytokine
storm is induced by the virus will be introduced in detail, including the ways in which cytokines

The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
… levels of pro-inflammatory cytokines are produced during the … in COVID-19, which has
linked the cytokine storm (CS) with the severe complications and poor outcomes in this infection. …

Targeting inflammation and cytokine storm in COVID-19

Q Huang, X Wu, X Zheng, S Luo, S Xu… - Pharmacological Research, 2020 - Elsevier
… considered as one of the options for COVID-19 patients with cytokine storm [4] based on their
… SARS-CoV-2 infection and subsequent release of virus particles recruits monocytes and …