Secondary hemophagocytic lymphohistiocytosis versus cytokine release syndrome in severe COVID-19 patients

NN Hakim, J Chi, C Olazagasti… - … Biology and Medicine, 2021 - journals.sagepub.com
… Although most of our COVID-19 patients did not fulfill diagnostic … of cytokine release. Based
on our observations, we would suggest distinguishing between cytokine release syndrome

Levels of the TNF-related cytokine LIGHT increase in hospitalized COVID-19 patients with cytokine release syndrome and ARDS

DS Perlin, I Zafir-Lavie, L Roadcap, S Raines… - MSphere, 2020 - Am Soc Microbiol
… Many coronavirus disease 2019 (COVID-19) patients demonstrate lethal respiratory
complications caused by cytokine release syndrome (CRS). Multiple cytokines have been …

[HTML][HTML] Utilizing tocilizumab for the treatment of cytokine release syndrome in COVID-19

A Hassoun, ED Thottacherry, J Muklewicz… - Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
… Interleukin 6 (IL-6) is one of the cytokines associated with ARDS related to COVID-19 and
it’… We present 9 patients with confirmed COVID-19 by detection of SARS-CoV 2 via reverse-…

[HTML][HTML] Role of IL-6 inhibitor in treatment of COVID-19-related cytokine release syndrome

P Du, J Geng, F Wang, X Chen, Z Huang… - International journal of …, 2021 - ncbi.nlm.nih.gov
… the IL-6 response in patients with COVID-19, clarified the pathogenesis of the role of IL-6-mediated
CRS in severe COVID-19, and highlighted the rationale for the use of anti-IL-6 agents …

[HTML][HTML] Tocilizumab in severe COVID-19 pneumonia and concomitant cytokine release syndrome

TDA van Kraaij, RLM Mostard, S Ramiro… - European journal of …, 2020 - ncbi.nlm.nih.gov
… There is no proven antiviral therapy for COVID-19 so far, but profound immunosuppression
COVID-19-associated CRS. We present a case of life-threatening CRS caused by COVID-19

A validated mathematical model of the cytokine release syndrome in severe COVID-19

RF Reis, AB Pigozzo, CRB Bonin… - Frontiers in molecular …, 2021 - frontiersin.org
By June 2021, a new contagious disease, the Coronavirus disease 2019 (COVID-19), has
infected more than 172 million people worldwide, causing more than 3.7 million deaths. Many …

Interleukin‑6 signaling blockade treatment for cytokine release syndrome in COVID19

JJ Chen, LN Zhang, H Hou… - Experimental and …, 2021 - spandidos-publications.com
coronavirus disease 2019 (COVID19) can cause a potentially lethal unconstrained inflammatory
cytokine storm, known as cytokine release syndrome … patients suffering from COVID19. …

Subcutaneous tocilizumab treatment in patients with severe COVID-19–related cytokine release syndrome: an observational cohort study

A Mastroianni, S Greco, G Apuzzo, S De Santis… - …, 2020 - thelancet.com
syndrome and pneumonia. Patients with severe COVID-19 have elevated levels of
inflammatory cytokines, … inflammatory response typical of cytokine release syndrome (CRS). We …

Biomarkers of cardiac stress and cytokine release syndrome in COVID-19: A review

JS Gordon, MH Drazner - Current heart failure reports, 2021 - Springer
… Myocardial injury in the setting of COVID-19 may lead to … microvascular dysfunction, and
cytokine release syndrome (CRS)-… ACovCS and cytokine release syndrome in COVID-19, with a …

Successful treatment of Covid-19 associated cytokine release syndrome with colchicine. A case report and review of literature

N Mansouri, M Marjani, P Tabarsi… - Immunological …, 2021 - Taylor & Francis
Covid-19 who despite improvement in his respiratory symptoms developed a mild to moderate
cytokine release syndrome … ferritin, D-dimer, and IL-6 levels normalized. To our knowledge…