Cytokine storm: the primary determinant for the pathophysiological evolution of COVID-19 deterioration

R Chen, Z Lan, J Ye, L Pang, Y Liu, W Wu… - Frontiers in …, 2021 - frontiersin.org
… cytokine storms promote the deterioration of COVID-19. Here, we outline the pathophysiological
processes through which cytokine storms contribute to the deterioration of SARS-CoV-2 …

COVID-19 pneumonia: pathophysiology and management

L Gattinoni, S Gattarello, I Steinberg… - European …, 2021 - Eur Respiratory Soc
COVID-19 from other forms of respiratory failure having similar gas exchange impairment and
… In figure 3 we summarise the time course of the evolution of COVID-19 we have observed, …

COVID-19: Current understanding of its Pathophysiology, Clinical presentation and Treatment

A Parasher - Postgraduate medical journal, 2021 - academic.oup.com
… The disease caused by this virus, termed coronavirus disease 19 or simply COVID-19, …
pathophysiology, clinical presentation and the most recent management strategies for COVID-19

The respiratory drive: an overlooked tile of COVID-19 pathophysiology

L Gattinoni, JJ Marini, L Camporota - American journal of respiratory …, 2020 - atsjournals.org
… Patients who experienced a deterioration in respiratory … Indeed, injury may be due either to
the natural evolution of COVID-19—… excessive respiratory drive may be relevant in COVID-19. …

The evolution of pulmonary pathology in fatal COVID-19 disease: an autopsy study with clinical correlation

H Bösmüller, S Traxler, M Bitzer, H Häberle, W Raiser… - Virchows Archiv, 2020 - Springer
… , underlying pathophysiologicalCOVID-19 is massive hypercoagulability with prominent
elevation of D-dimer and fibrin/fibrin degradation products as in patients 2 and 3 [17,18,19]. This …

Identification of pathophysiological patterns for triage and respiratory support in COVID-19

L Camporota, F Vasques, B Sanderson… - The Lancet …, 2020 - thelancet.com
evolving understanding of the pathophysiology and natural history of this new disease.
COVID-19 … induced lung injury, are prone to further deterioration with non-invasive ventilation (NIV…

Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (COVID-19): a review

WJ Wiersinga, A Rhodes, AC Cheng, SJ Peacock… - Jama, 2020 - jamanetwork.com
… be that the pathophysiology is summarized … pathophysiology and it is meant for a general
readership. We attempted to create an overview of the pathophysiology underlying COVID-19

A scoping review of the pathophysiology of COVID-19

PE Marik, J Iglesias, J Varon… - International journal of …, 2021 - journals.sagepub.com
… While multiple biological pathways and processes underlie the pulmonary phase of COVID-19,
we believe that two major pathogenetic processes cause severe COVID-19, namely i) the …

The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
… We review the intricacies of COVID-19 pathophysiologyCOVID-19 and respiratory failure
of other origins, but evidence for many distinctive mechanistic features indicates that COVID-19

SARS-CoV-2/COVID-19: evolving reality, global response, knowledge gaps, and opportunities

MF Osuchowski, F Aletti, JM Cavaillon, SB Flohe… - Shock, 2020 - journals.lww.com
… 2/COVID-19 remains scarce; there is an urgent need to expand our understanding of the
SARS-CoV-2 pathophysiology to … Renal dysfunction may be an early sign for later deterioration. …