[HTML][HTML] Impacts of Inflammatory Cytokines Variants on Systemic Inflammatory Profile and COVID-19 Severity

XJ Deng, K Tang, Z Wang, S He, Z Luo - Journal of Epidemiology and …, 2024 - Springer
… In addition, the A allele of rs1800629 increased the severity and mortality of COVID-19. …
The present study showed that pro-inflammatory cytokines variants remodeled the systemic …

[HTML][HTML] The systemic inflammation index on admission predicts in-hospital mortality in COVID-19 patients

AG Fois, P Paliogiannis, V Scano, S Cau, S Babudieri… - Molecules, 2020 - mdpi.com
pro-inflammatory state followed by acute respiratory distress syndrome is the leading cause
of mortality in patients with COVID-19. … severe COVID-19 patients to a cytokine storm, thus …

[HTML][HTML] Cytokine signature associated with disease severity in COVID-19

J Guo, S Wang, H Xia, D Shi, Y Chen, S Zheng… - Frontiers in …, 2021 - frontiersin.org
… is the leading cause of mortality for COVID-19 patients (5). Hypercytokinemia, which is
also called … Both anti-inflammatory cytokines (such as IL-10 and IL-13) and pro-inflammatory

[HTML][HTML] Pro-and anti-inflammatory responses in severe COVID-19-induced acute respiratory distress syndrome—an observational pilot study

Q Notz, M Schmalzing, F Wedekink… - Frontiers in …, 2020 - frontiersin.org
COVID-19-induced ARDS. We are the first to exclusively characterize a COVID-19 ICU patient
population with an expected mortality … to the production of pro-inflammatory cytokines (ie IL…

Factors leading to high morbidity and mortality of COVID19 in patients with type 2 diabetes

A Rajpal, L Rahimi, F Ismail‐Beigi - Journal of diabetes, 2020 - Wiley Online Library
… patients with T2DM who develop COVID-19. However, many … morbidity and mortality of
patients with T2DM and COVID-19. … pro-inflammatory cytokines contribute to severe COVID-19. …

[HTML][HTML] Scoring cytokine storm by the levels of MCP-3 and IL-8 accurately distinguished COVID-19 patients with high mortality

L Chen, G Wang, J Tan, Y Cao, X Long, H Luo… - … and Targeted Therapy, 2020 - nature.com
cytokines in a total of 181 COVID-19 patients (training and internal test sets). The cytokine
… The levels of 17 pro-inflammatory cytokines, including IL-8, IP-10, MCP-1, MCP-3, MIP-1α, IL…

Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality

C Zhang, Z Wu, JW Li, H Zhao, GQ Wang - International journal of …, 2020 - Elsevier
… It is a multi-effective cytokine with both anti-inflammatory and pro-inflammatory effects. There
are three main pathways of IL-6 signal transduction [14,17]: (i) classical signal transduction (…

Analysis of serum cytokine and protective vitamin D levels in severe cases of COVID19

N Bayraktar, H Turan, M Bayraktar… - Journal of medical …, 2022 - Wiley Online Library
COVID-19 patients are associated with lower serum vitamin D and higher pro-inflammatory
cytokines … million confirmed cases of COVID-19, more than four million deaths, and nearly …

Indicators of critical illness and predictors of mortality in COVID-19 patients

MH Aly, SS Rahman, WA Ahmed… - Infection and drug …, 2020 - Taylor & Francis
… with mortality of COVID-19. High levels of d-dimer have been associated with 28-day mortality
in … Citation23 The other mechanisms include the pro-inflammatory cytokine responses that …

[HTML][HTML] The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”

GH Meftahi, Z Jangravi, H Sahraei, Z Bahari - Inflammation Research, 2020 - Springer
… generation of pro-inflammatory cytokines. The mortality rate for young adults with COVID-19
(… However, the mortality rate for obese elderly adults with COVID-19 was approximately 14% […