… for IL-6 blockade. Then, we discuss in detail the relevance of IL-6 in the pathophysiology of
COVID-19 … The safety and efficacy of IL-6 pathway inhibition in COVID-19 is also extensively …

… Given the efficacy of tocilizumab in CRS and the pivotal role of IL-6 in COVID-19, we propose
to repurpose tocilizumab to treat severe cases of COVID-19. Regarding its clinical use, we …

… IL-6 is also a robust marker for predicting disease prognosis and deterioration of clinical …
role played by IL-6 in the immuno-pathology of COVID-19 has been illustrated. The role of IL-6 …

… cytokine storm of COVID-19 and the value of cytokines in diagnosis and treatment of the
COVID-19. … highlights the importance of IL-6 and IL-10 as COVID-19 disease severity predictors. …

… produced by IL-6 as the main inflammatory mediator in patients with COVID-19 with severe
… poor prognosis of these patients with increased IL-6 levels in the context of cytokine release …

… Based on our results, IL‐6 is an important marker of inflammation and … COVID‐19 early in
the disease course. Furthermore, researchers should develop a scoring system including IL‐6 …

… , approximately 19% of cases of COVID-19 are severe or critical. … with COVID-19 [2].
Additionally, pathological examination of a biopsy sample from a patient who died from COVID-19 …

… with MAS/sHLH may be driving COVID-19 related ARDS has created a tremendous … COVID-19
pulmonary immunopathology and describe the potential benefits or disadvantages of IL-6 …

… purpose of this study is to explore changes of markers in peripheral blood of severe COVID-19
… Since we have found that IL-6 is related to COVID-19 severity, we suggest that targeting …

… of COVID-19 in our own centre, when IL-6 was being measured for research purposes rather
than clinical care, we used the following criteria for COVID-CSS: 1) COVID-19 pneumonia …