[HTML][HTML] Preventing cytokine storm syndrome in COVID-19 using α-1 adrenergic receptor antagonists

MF Konig, M Powell, V Staedtke, RY Bai… - The Journal of …, 2020 - Am Soc Clin Investig
… or critical COVID-19 treated with tocilizumab suggest that inhibiting the IL-6 signaling axis
may reduce patient morbidity and the need for mechanical ventilation (24) but may fail to treat

[HTML][HTML] A promising anti-cytokine-storm targeted therapy for COVID-19: the artificial-liver blood-purification system

Y Zhang, L Yu, LL Tang, M Zhu, Y Jin… - Engineering (Beijing …, 2021 - ncbi.nlm.nih.gov
… Blood-Purification System in the treatment of severe COVID-19 was recently released [22]. …
for the treatment of patients with COVID-19 infection who exhibit cytokine storm and rapid …

Cytokine storm in COVID19 and parthenolide: Preclinical evidence

M Bahrami, M Kamalinejad, SA Latifi… - Phytotherapy …, 2020 - Wiley Online Library
… Although specific blockade of pro-inflammatory cytokines using mAbs is one of the main
therapeutic strategies for the management of cytokine storm in COVID19, parthenolide may be …

Treatment for COVID-19: An overview

C Stasi, S Fallani, F Voller, C Silvestri - European journal of pharmacology, 2020 - Elsevier
… and pneumonia; the third by a worsening clinical scenario dominated by a cytokine storm
and the consequent hyperinflammatory state; and the fourth by death or recovery. Currently, no …

Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: results from a single Italian Centre study on tocilizumab versus standard of care

L Quartuccio, A Sonaglia, D McGonagle… - Journal of Clinical …, 2020 - Elsevier
… To conclude, our study showed that TOCI treated patients COVID-19 pneumonia were at
the highest risk of cytokine storm [32]. However, long-term data are reassuring, overall fatality …

COVID-19: more than a cytokine storm

G Riva, V Nasillo, E Tagliafico, T Trenti, P Comoli… - Critical care, 2020 - Springer
… In this view, COVID-19-associated cytokine storm, with elevated plasma levels of IL-6, IL-1, …
but the other “key feature” of COVID-19—the progressive lymphopenia with T cell exhaustion […

[HTML][HTML] Covid19: time for a paradigm change

FM Buonaguro, PA Ascierto, GD Morse… - Reviews in medical …, 2020 - ncbi.nlm.nih.gov
… severe Covid19 might have a cytokine storm syndrome. We recommend identification and
treatment … The conventional treatment of patients with viral infection has been antipyretic and …

Prevention of the cytokine storm in COVID-19

DJM Wright - The Lancet Infectious Diseases, 2021 - thelancet.com
… of a cytokine storm, induced by treatment of relapsing fever … for COVID-19 in patients
presenting with a cytokine storm and … in the context of the COVID-19 cytokine storm, to establish if …

[HTML][HTML] Are mesenchymal stem cells able to manage cytokine storm in COVID-19 patients? A review of recent studies

NK Farkhad, H Reihani, AA Moghadam… - … Therapy, 2021 - Elsevier
… This review paper aims to investigate the role of MSCs in reducing and managing cytokine
storms in Covid-19 patients based on summarizing the available results from recent studies …

[PDF][PDF] Coronavirus-19 (SARS-CoV-2) induces acute severe lung inflammation via IL-1 causing cytokine storm in COVID-19: a promising inhibitory strategy

P Conti, A Caraffa, CE Gallenga, R Ross… - J Biol Regul Homeost …, 2020 - researchgate.net
COVID-19. Here, we propos for the first time that IL-37, by blocking IL-1, may have an important
role in the therapy of COVID-19. … the treatment of cytokine storm syndrome in COVID-19. …