[HTML][HTML] Dapagliflozin in patients with chronic kidney disease

HJL Heerspink, BV Stefánsson… - … England Journal of …, 2020 - Mass Medical Soc
chronic kidney disease, with or without type 2 diabetes, who were randomly assigned to
receive dapagliflozin … GFR of at least 50%, end-stage kidney disease, or death from renal or …

Effects of dapagliflozin in stage 4 chronic kidney disease

GM Chertow, P Vart, N Jongs, RD Toto… - Journal of the …, 2021 - journals.lww.com
… trial, we show beneficial effects of dapagliflozin on kidney and cardiovascular end points in
… significant attenuation of loss of kidney function as reflected by the eGFR slopes over time. …

Effect of dapagliflozin on clinical outcomes in patients with chronic kidney disease, with and without cardiovascular disease

JJV McMurray, DC Wheeler, BV Stefánsson, N Jongs… - Circulation, 2021 - Am Heart Assoc
… of dapagliflozin on the prespecified kidney and cardiovascular outcomes in patients with
chronic kidney disease … of cardiovascular disease, in the DAPA-CKD trial (Dapagliflozin and …

Dapagliflozin for the treatment of chronic kidney disease

Y Kurata, M Nangaku - Expert Review of Endocrinology & …, 2022 - Taylor & Francis
… Among SGLT2is, dapagliflozin was the first to demonstrate the renoprotective effect in
patients with and without diabetes and has been approved for chronic kidney disease (CKD) …

The dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial: baseline characteristics

DC Wheeler, BV Stefansson, M Batiushin… - Nephrology Dialysis …, 2020 - academic.oup.com
… other trials in this field, the DAPA-CKD trial will provide unique insights into whether dapagliflozin
confers kidney protection in patients with CKD and diverse kidney disease aetiologies. …

Effect of dapagliflozin on the rate of decline in kidney function in patients with chronic kidney disease with and without type 2 diabetes: a prespecified analysis from the …

HJL Heerspink, N Jongs, GM Chertow… - The lancet Diabetes & …, 2021 - thelancet.com
Dapagliflozin significantly slowed long-term eGFR decline in patients with chronic kidney
disease … The mean difference in eGFR slope between patients treated with dapagliflozin versus …

Efficacy and safety of dapagliflozin in patients with type 2 diabetes and moderate renal impairment (chronic kidney disease stage 3A): The DERIVE Study

P Fioretto, S Del Prato, JB Buse… - Diabetes, Obesity …, 2018 - Wiley Online Library
Dapagliflozin is a selective inhibitor of sodium glucose co-transporter 2 (SGLT2). This study
assessed the efficacy and safety of dapagliflozin … 2 ; chronic kidney disease [CKD] stage 3A). …

Effects of dapagliflozin on major adverse kidney and cardiovascular events in patients with diabetic and non-diabetic chronic kidney disease: a prespecified analysis …

DC Wheeler, BV Stefánsson, N Jongs… - The lancet Diabetes & …, 2021 - thelancet.com
… with chronic kidney disease. We aimed to investigate the effects of dapagliflozin on kidney,
… according to underlying cause of chronic kidney disease, reported as diabetic nephropathy, …

Effects of dapagliflozin in patients with kidney disease, with and without heart failure

JJV McMurray, DC Wheeler, BV Stefánsson, N Jongs… - Heart Failure, 2021 - jacc.org
dapagliflozin in chronic kidney disease (CKD) patients, with and without heart failure (HF). …
Heart failure (HF) is common in patients with chronic kidney disease (CKD), reflecting the high …

Effects of the SGLT2 inhibitor dapagliflozin on proteinuria in non-diabetic patients with chronic kidney disease (DIAMOND): a randomised, double-blind, crossover trial

DZI Cherney, CCJ Dekkers, SJ Barbour… - The lancet Diabetes & …, 2020 - thelancet.com
kidney effects of the SGLT2 inhibitor dapagliflozin in patients with proteinuric kidney disease
… did not affect proteinuria in patients with chronic kidney disease without diabetes, but did …