GM Chertow, P Vart, N Jongs, RD Toto… - Journal of the …, 2021 - journals.lww.com
… trial, we show beneficial effects of dapagliflozin on kidney and cardiovascular end points in … significant attenuation of loss of kidney function as reflected by the eGFR slopes over time. …
JJV McMurray, DC Wheeler, BV Stefánsson, N Jongs… - Circulation, 2021 - Am Heart Assoc
… of dapagliflozin on the prespecified kidney and cardiovascular outcomes in patients with chronickidneydisease … of cardiovascular disease, in the DAPA-CKD trial (Dapagliflozin and …
Y Kurata, M Nangaku - Expert Review of Endocrinology & …, 2022 - Taylor & Francis
… Among SGLT2is, dapagliflozin was the first to demonstrate the renoprotective effect in patients with and without diabetes and has been approved for chronickidneydisease (CKD) …
DC Wheeler, BV Stefansson, M Batiushin… - Nephrology Dialysis …, 2020 - academic.oup.com
… other trials in this field, the DAPA-CKD trial will provide unique insights into whether dapagliflozin confers kidney protection in patients with CKD and diverse kidneydisease aetiologies. …
HJL Heerspink, N Jongs, GM Chertow… - The lancet Diabetes & …, 2021 - thelancet.com
… Dapagliflozin significantly slowed long-term eGFR decline in patients with chronickidney disease … The mean difference in eGFR slope between patients treated with dapagliflozin versus …
P Fioretto, S Del Prato, JB Buse… - Diabetes, Obesity …, 2018 - Wiley Online Library
… Dapagliflozin is a selective inhibitor of sodium glucose co-transporter 2 (SGLT2). This study assessed the efficacy and safety of dapagliflozin … 2 ; chronickidneydisease [CKD] stage 3A). …
DC Wheeler, BV Stefánsson, N Jongs… - The lancet Diabetes & …, 2021 - thelancet.com
… with chronickidneydisease. We aimed to investigate the effects of dapagliflozin on kidney, … according to underlying cause of chronickidneydisease, reported as diabetic nephropathy, …
JJV McMurray, DC Wheeler, BV Stefánsson, N Jongs… - Heart Failure, 2021 - jacc.org
… dapagliflozin in chronickidneydisease (CKD) patients, with and without heart failure (HF). … Heart failure (HF) is common in patients with chronickidneydisease (CKD), reflecting the high …
… kidney effects of the SGLT2 inhibitor dapagliflozin in patients with proteinuric kidneydisease … did not affect proteinuria in patients with chronickidneydisease without diabetes, but did …