Defining the genetic blueprint of kidney development

SS Potter, EW Brunskill, LT Patterson - Pediatric Nephrology, 2011 - Springer
gene expression strategies to study kidney development. … in kidney development, provide
new molecular markers to aid in the analysis of mutant phenotypes, lend insight into genetic

Defining Genetic BlueprintsKidney and Craniofacial Development

EW Brunskill, AS Potter, SS Potter - Pediatric Biomedical Informatics …, 2012 - Springer
… of the forming kidney when one could not be sure which genes were being … gene expression
patterns in order to generate a useful genomics level understanding of kidney development

Atlas of gene expression in the developing kidney at microanatomic resolution

EW Brunskill, BJ Aronow, K Georgas, B Rumballe… - Developmental cell, 2008 - cell.com
gene expression atlas of the developing mouse kidney based on … This kidney atlas allows a
comprehensive analysis of the … view of the gene expression blueprint of kidney development. …

[HTML][HTML] A transcriptional blueprint for human and murine diabetic kidney disease

V Bhalla, MG Velez, GM Chertow - Diabetes, 2013 - ncbi.nlm.nih.gov
… and kidney disease are … ), kidney disease in patients with diabetes is crudely defined. This
work may help to redefine the taxonomy of diabetic kidney disease based on glomerular gene

Normal and abnormal development of the kidney: a clinician's interpretation of current knowledge

KI Glassberg - The Journal of urology, 2002 - Elsevier
… with new discoveries in the molecular genetics of renal development. However, little of this
… and propose a more sophisticated blueprint of renal development than the one traditionally …

[HTML][HTML] A blueprint for randomized trials targeting phosphorus metabolism in chronic kidney disease

T Isakova, OM Gutiérrez, M Wolf - Kidney international, 2009 - Elsevier
… We propose a first-draft of a blueprint of potential randomized, controlled trials of different
phosphorus management strategies aimed at improving survival in CKD. Although the optimal …

Multidisciplinary approaches for elucidating genetics and molecular pathogenesis of urinary tract malformations

K Khan, DF Ahram, YP Liu, R Westland… - Kidney international, 2022 - Elsevier
… Here, we review recent multidisciplinary approaches at the intersection of genetics,
genomics, in vivo modeling, and in vitro systems toward refining a blueprint for overcoming the …

Gene regulatory network of renal primordium development

M Marcotte, R Sharma, M Bouchard - Pediatric nephrology, 2014 - Springer
… in the activation of additional regulators of kidney development, including Lim1, Sal1 and …
, we are now in a position to establish a blueprint of the GRN driving early renal lineage …

The evolving role of genetic testing in monogenic kidney stone disease: spotlight on primary hyperoxaluria

MC Breeggemann, PC Harris, JC Lieske… - The Journal of …, 2024 - auajournals.org
… screening panel (Invitae) and a 45-gene screening panel (Blueprint Genetics) can be used
and is covered by the Alnylam Act and NovoDETECT, respectively. For sponsored testing, …

Genetic determination of nephrogenesis: the Pax/Eya/Six gene network

S Brodbeck, C Englert - Pediatric nephrology, 2004 - Springer
… The first sign of kidney development is the interaction … genes that play a crucial role in early
kidney development, such as Pax2, Eya1, Six1, Six2, Sall1, Foxc1, Wt1, and the Hox11 genes