Cytokine storm is the cryptic killer behind coronavirus disease-2019 infections, review of the current evidence to identify therapeutic options

D Alrahmany, IM Ghazi - Reviews and Research in Medical …, 2021 - journals.lww.com
… The objective of this article is to review the involvement of inflammatory mediators in
cytokine storm syndrome (CSS) and highlight the possibility of … The cytokine storm syndrome …

[PDF][PDF] Mechanism of Cytokine Storm in COVID-19: How can probiotics combat it

MS Reddy - JAAPI, 2021 - aapiusa.org
… definition, cytokine storm is an activation cascade of auto-amplifying cytokine production due
to … Before we proceed with the pathophysiology of COVID-19 induced cytokine storm, it is …

Cascade of immune mechanism and consequences of inflammatory disorders

KB Megha, X Joseph, V Akhil, PV Mohanan - Phytomedicine, 2021 - Elsevier
… -associated autoimmunity, immunopathology and allergic … for cytokine storm has become
an essential part of rescuing severe patients. The specific phenomenon namely the cytokine

Is there a link between the pathogenic human coronavirus envelope protein and immunopathology? A review of the literature

D Schoeman, BC Fielding - Frontiers in microbiology, 2020 - frontiersin.org
… -CoV-2 E protein in the cytokine storm, and the consequent immunopathology of COVID-19, …
for the cytokine storm induction and the consequent immunopathology often seen in severe …

The immunopathological and histological landscape of COVID-19-mediated lung injury

G Zarrilli, V Angerilli, G Businello, M Sbaraglia… - International Journal of …, 2021 - mdpi.com
immunopathological mechanisms of … The immunopathological scenario of COVID-19 is
poorly characterized as well. The so-called cytokine storm has been proposed as a mechanism

Coronavirus disease-2019: A review on the disease exacerbation via cytokine storm and concurrent management

H Sunkara, SMR Dewan - International immunopharmacology, 2021 - Elsevier
… In this review, we focused on the current treatment approaches targeting the crucial
causative factors for the disease burden through cytokine storm or cytokine release syndrome. …

Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy?

LYR Wong, S Perlman - Nature Reviews Immunology, 2022 - nature.com
… of the mechanisms involved in each of these scenarios. … scientists have described the
immunopathological nature of immune … We also describe and discuss the immunopathological

[PDF][PDF] Treatment of the Cytokine Storm in COVID-19

B Halacli, A Topeli - J Crit Intensive Care, 2020 - researchgate.net
… In the light of the steadily learned knowledge about immunopathology of especially severe
phenotypes … condition so-called “cytokine storm” which might be observed during COVID-19. …

Excitotoxicity (immunoexcitotoxicity) as a critical component of the cytokine storm reaction in pulmonary viral infections, including SARS-CoV-2

RL Blaylock - International Journal of Vaccine Theory, Practice, and …, 2021 - mail.ijvtpr.com
cytokines, by themselves, may not be sufficient to cause the pathological damage that we
see in cases of cytokine storm is … cytokines and chemokines is an early event in the cytokine

The immune response and immunopathology of COVID-19

E Mortaz, P Tabarsi, M Varahram, G Folkerts… - Frontiers in …, 2020 - frontiersin.org
… being the common immunopathological event for SARS-CoV-2, SARS-CoV, and MERS-CoV
infections is unclear although it probably involves the generation of a cytokine storm (68). …