… The respiratory tract is a major barrier tissue and is often the … The principal lethal
threats for patients with COVID-19 are … as a cytokine storm. Age-related increases in pro-inflammatory …

… Coronaviruses have posed a global threat to public health. … Citation42 Cytokine storm or
cytokine storm syndrome (CSS), … Increased cytokine production is a major contributory factor …

… They are produced by the virus infected cells to signal the neighboring cells regarding viral
infection threat. The examples for … The lL-6 plays a major role as pro-inflammatory cytokine. …

… Administration of apoptotic cells to patients with mild-to-moderate sepsis was safe and
had a significant immuno-modulating effect, leading to early resolution of the cytokine storm. …

… of cytokines. The antioxidant defense mechanism in the body helps in counteracting symptoms
induced by the cytokine storm … therapeutic use in managing cytokine storm in COVID-19. …

… Cytokine storm (CS) is primarily observed in cases of sepsis and infectious diseases, … threat
to human life and a major concern for the WHO. An overview of immune cells and cytokines …

… cytokine storm. Likewise, it attempts to summarize the main findings related to the powerful
effects of melatonin and some micronutrients (vitamins and minerals), which may be useful (…

… ) inflammasome are the major cause of inflammatory cytokine storm, and thereby clinical …
are implicated in inflammatory cytokine storm and inflammatory complex including IL-6, tumor …

… Importantly, HLH has been recognized as a severe variation of the cytokine storm associated
with COVID-19. Common features include a history of infection or malignancy, fever, …

… major threat … Cytokine storm is considered to be one of the main reasons of ARDS and
multiple organ failure. [3] It plays an important role in making the disease worse. [4] Cytokine storm …