Analysis of Multiple Plasmodium falciparum Infections in Tanzanian Children during the Phase III Trial of the Malaria Vaccine SPf66

HP Beck, I Felger, W Huber, S Steiger… - Journal of Infectious …, 1997 - academic.oup.com
… of the malaria vaccine SPf66 in Africa, MOIs in SPf66- and placebo-vaccinated children were
… MOIs were significantly reduced in asymptomatic vaccine recipients compared with those in …

Evaluation of the SPf66 vaccine for malaria control when delivered through the EPI scheme in Tanzania

CJ Acosta, CM Galindo, D Schellenberg… - Tropical Medicine & …, 1999 - Wiley Online Library
… As part of the programme to evaluate SPf66 as a potential tool for malaria control in Africa, …
However, SPf66 did not reduce the risk of clinical malaria among Tanzanian children living …

Efficacy trial of malaria vaccine SPf66 in Gambian infants

U D'alessandro, A Leach, BO Olaleye, GW Fegan… - The lancet, 1995 - thelancet.com
… index of malaria were found between the two groups of children. … on SPf66 efficacy from
South America and from Tanzania. In … of malaria during the rainy season after immunisation in …

Immune responses to Plasmodium falciparum antigens during a malaria vaccine trial in Tanzanian children

ALONSO, LOPEZ, BORDMANN, SMITH… - Parasite …, 1998 - Wiley Online Library
… merozoite derived sequences contained in the malaria vaccine SPf66 (83.1, 55.1 and 35.1)
… the SPf66 vaccine induce a strong IgG antibody response against both the SPf66 construct, …

Humoral immune responses during a malaria vaccine trial in Tanzanian infants

Galindo, Acosta, Schellenberg, Aponte… - Parasite …, 2000 - Wiley Online Library
… We have completed a trial of the peptide vaccine SPf66 in Tanzanian infants, given … of
the effects of the SPf66 malaria vaccine in African children exposed to intense transmission of …

[PDF][PDF] Efficacy of SPf66 vaccine against Plasmodium falciparum malaria in children

JF Trape, C Rogier, PL Alonso, T Smith… - …, 1995 - horizon.documentation.ird.fr
… of clinical malaria among Tanzanian children who had received the SPf66 malaria vaccine
developed by Pattaroyo. These results were obtained in an area where malaria transmission …

Duration of protection and age-dependence of the effects of the SPf66 malaria vaccine in African children exposed to intense transmission of Plasmodium falciparum

PL Alonso, TA Smith… - Journal of Infectious …, 1996 - academic.oup.com
… -up, while further supplies of SPf66 were prepared and transported to Tanzania. In the first
week of February 1995, SPf66 was offered to children who had previously received placebo, …

Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand

F Nosten, C Luxemburger, DE Kyle, WR Ballou… - The lancet, 1996 - thelancet.com
… America and evidence of borderline efficacy from Tanzania. We conclude that SPf66 does
not protect against clinical falciparum malaria and that further efficacy trials are not warranted. …

[PDF][PDF] Malaria vaccine in children under 12 months of age

K Mulholland, U D'Alessandro, S Allen, B Genton… - The Lancet, 1995 - academia.edu
… first field trial of the SPf66 malaria vaccine in children under 12 months of … malaria vaccine
SPf66 in Tanzanian children’ and Gambian infants (D’Alessandro and colleagues), vaccine

Safety in infants of SPf66, a synthetic malaria vaccine, delivered alongside the EPI

DM Schellenberg, CJ Acosta… - Tropical Medicine & …, 1999 - Wiley Online Library
… In Tanzania, SPf66 reduced the risk of clinical malaria by 31% in children aged 1–5 years. …
development and testing towards the implementation of a new vaccine in malaria control …