Mammalian kidney development: principles, progress, and projections

MH Little, AP McMahon - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
… in maturation of mammalian kidney function, there is also a significant disconnect between
our understanding of fetal kidney development and the normal response of the adult kidney to …

Development of the mammalian kidney

AP McMahon - Current topics in developmental biology, 2016 - Elsevier
… This framework is now guiding studies of human kidney development enabled in part by in
vitro … about kidney development comes from studies of only two mammals: the rat and mouse. …

[图书][B] Factors influencing mammalian kidney development: implications for health in adult life

KM Moritz, JF Bertram, MJ Black, G Caruana… - 2008 - Springer
… The development of the permanent mammalian kidney (metanephros) is initiated with the
outgrowth of the UB from the caudal end of the WD. This occurs at approximately day 30 in …

The cellular basis of kidney development

GR Dressler - Annu. Rev. Cell Dev. Biol., 2006 - annualreviews.org
Mammalian kidney development has helped elucidate the general concepts of
mesenchymal-epithelial interactions, inductive signaling, epithelial cell polarization, and branching …

Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development

KR Schwab, LT Patterson, HA Hartman, N Song… - BMC biology, 2007 - Springer
… The mammalian Pygopus genes are required for normal branching morphogenesis of the …
during kidney development. Nevertheless, the relatively mild phenotype observed in the kidney

The origin of the mammalian kidney: implications for recreating the kidney in vitro

M Takasato, MH Little - Development, 2015 - journals.biologists.com
… of kidney development, the end results and their interpretation varied. This suggests a need
for a careful reanalysis of our current understanding of kidney development. In … development. …

Growth and death in the developing mammalian kidney: signals, receptors and conversations

JBL Bard - Bioessays, 2002 - Wiley Online Library
development. Growth deserves more attention than it usually receives and the purpose of
this article is to reconsider the normal story of kidney development, but from a growth …

Mesenchyme to epithelium transition during development of the mammalian kidney tubule

JA Davies - Cells Tissues Organs, 1996 - karger.com
Kidney epithelia have two separate origins. Collecting ducts develop in the manner of most
… Excretory tubules develop by a direct mesenchyme to epithelium transition (MET), which is …

Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development

A Kobayashi, MT Valerius, JW Mugford, TJ Carroll… - Cell stem cell, 2008 - cell.com
… To determine whether Six2+ cells similarly contribute to nephron formation at later stages in
kidney development, we used the GCE allele for tamoxifen-dependent labeling of Six2+ cells…

Control of mammalian kidney development by the Hedgehog signaling pathway

JE Cain, ND Rosenblum - Pediatric nephrology, 2011 - Springer
mammalian kidney development. The use of genetic murine models exhibiting aberrant Hh
signaling has indicated that a fine balance between GLI activator and GLI repressor activity …