miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial–mesenchymal transition in pterygium
DH Engelsvold, TP Utheim, OK Olstad… - Experimental eye …, 2013 - Elsevier
The current study investigates whether microRNA (miRNA) regulators of epithelial–
mesenchymal transition (EMT), tissue fibrosis, and angiogenesis are differentially expressed
in human primary pterygium. Genome-wide miRNA and mRNA expression profiling of
paired pterygium and normal conjunctiva was performed in the context of conventional
excision of pterygium with autotransplantation of conjunctiva (n= 8). Quantitative real time
polymerase chain reaction (qRT-PCR) was used to validate the expression of key molecules …
mesenchymal transition (EMT), tissue fibrosis, and angiogenesis are differentially expressed
in human primary pterygium. Genome-wide miRNA and mRNA expression profiling of
paired pterygium and normal conjunctiva was performed in the context of conventional
excision of pterygium with autotransplantation of conjunctiva (n= 8). Quantitative real time
polymerase chain reaction (qRT-PCR) was used to validate the expression of key molecules …
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