… nephron progenitor cells (NPCs) that can form nephron-like structures. By recapitulating
metanephric kidney development … + renal vesicles that self-organize into nephron structures. In …

… Herein, using cell sorting, RNA sequencing, in vitro … human kidney development and
tumorigenesis; In nephrogenesis, NCAM1 + CD133 − marks SIX2 + multipotent renal stem cells …

… -restricted progeny drive nephron formation within the developing kidney. Here, … stem cell
marker Lgr5 in the developing kidney and assess the stem/progenitor identity of Lgr5 +ve cells …

… The aim of this paper is to review human kidney organogenesis, … peculiarities of nephron
progenitor populations and on the … no postnatal renal stem cell is capable of true nephron …

… The first stepping stone was the anatomic description of human kidney development.
There are … Generation of functioning nephrons by implanting human pluripotent stem cell-derived …

… Human pluripotent stem cells (hPSCs) hold great promise for understanding kidney
development and disease. We reproducibly differentiated three genetically distinct wild-type hPSC …

… Studies of kidney development in vivo have also facilitated … mouse kidney, including a reduced
number of progenitor cells … earlier human kidney, and the existence of multiple nephrons …

… to develop a high-efficiency protocol to generate nephron progenitor cells (NPCs) and kidney
… that draw upon our knowledge of kidney development to differentiate PSCs into cells of the …

… Once nephron epithelia are formed the view of post-MET tissue renal growth and … Although
the exact developmental stage to which NCAM1 + nephron progenitor cells correspond still …

… in the human kidney is completed before birth 5 . Hence, there is no postnatal stem cell able
to replace lost nephrons. … However, normal kidney development involves a careful balance …